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a chemical compound e.g., a VLSEPS peptide anay, polynucleotide anay, and/or combinatorial small molecule anay biological macromolecule e.g., a VLSEPS peptide anay, polynucleotide anay, and/or combinatorial small molecule anay Agents are evaluated for potential activity as anti-neoplasties, anti-inflammatories or apoptosis modulators by inclusion in screening assays described hereinbelow

doi: 10.1093/jxb/eri167 93 YoungJ

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The cell suspension was passed through a 40 m nylon mesh, centrifuged (300 g for 7 min at room temperature) and resuspended in PBS supplemented with BSA

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Monitoring requirements: Glucose levels (may affect glucose tolerance), IGF-1 levels (to assess response and safety)