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Micro-lesions in the plasma membrane result in Ca 2+ entry, triggering the recruitment of vesicles to the damaged area

However, melatonin has demonstrated satisfactory results in terms of being a possible prophylactic measure for COVID-19 infection (141)

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Regarding the former, unlike single-antigen vaccines such as peptide-based formulations, whole-cell vaccines retain the full antigenic repertoire of tumor cells, enabling simultaneous activation of polyclonal T cell responses against multiple antigens and thereby reducing the likelihood of immune escape