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Are Animal Models Useful for Studying Human Disc Disorders/degeneration

Fox SR, Jong MT, Casanova J, Ye ZS, Stanley F, Samuels HH

10.1073/pnas.1305411110 9 BramhallN

Vitamin B6 is necessary for the production of serotonin and dopamine, which are neurotransmitters dedicated to regulating our moods and stabilising our emotions

Adeno-associated viral vector (Serotype 2)-nerve growth factor for patients with Alzheimer disease

First, optimal dosing in humans remains undefined, with current practice based primarily on extrapolation from animal studies and anecdotal clinical experience rather than formal dose-finding studies