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Lindy, S., Uitto, J., Turto, H., Rokkanen, P

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In KRAS mutant models, macrophages promote copper uptake via a non-classical pathway to supply bioavailable copper for tumor growth, while ATP7A alleviates copper toxicity through efflux mechanisms

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Using the targeting of nanoparticles, the encapsulated engineered bacteria can specifically aggregate at the tumor site of HCC [145]

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