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10.3389/fgene.2023.1166831 406 XieY.HouW.SongX.YuY.HuangJ.SunX.et al

It reduced magnetic resonance imaging-proton density fat fraction (MRI-PDFF) by -20.266 (95% CI: -35.806 to -4.726, P=0.01) and decreased enhanced liver fibrosis score (baseline 9) by -0.234 (95% CI: -0.441 to -0.027, P=0.03)

Furthermore, pharmacological inhibition of the responsible DNA repair enzyme O 6 -methylguanine DNA methyltransferase (MGMT) increases the sensitivity of test systems to detect O 6 -methylguanine-triggered DNA strand breaks (Carlsson et al