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10.3164/jcbn.15-148 163

This abnormal methylation pattern leads to genome-wide instability and altered gene expression profiles (Liang and Weisenberger, 2017)

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Data was analyzed using Spectronaut V15.7.2 (Biognosys AG) direct DIA analysis using an isoform Rat database (UniProt downloaded 22.02.2021) consisting of 9,746 protein entries utilizing the Pulsar search engine

The design of Rg1 nanoparticles enables enhanced blood-brain barrier permeability, facilitating targeted treatment to affected regions, thus improving the therapeutic outcomes ( Network pharmacology analysis There exists a substantial obstacle in bringing Rg1 to clinical practice due to the requirement to demonstrate consistent research results that apply to the broad patient population