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Song EK, Hur H, Han MK: Epigallocatechin gallate prevents autoimmune diabetes induced by multiple low doses of streptozotocin in mice

Some combinations may synergize while others offer diminishing returns or potential interactions

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Phase I, dose-escalation, two-Part Trial of the PARP inhibitor talazoparib in patients with advanced germline BRCA1/2 mutations and selected sporadic cancers

In response to the dopaminergic neural activation induced by substances of abuse, such as heroin (119, 120), methamphetamine (121, 122), and cocaine (123), the mitochondrial respiratory chain is rapidly activated, leading to mitochondrial dysfunction, such as decreased mitochondrial membrane potential, mitochondrial DNA, and mitochondrial proteins, and increased cytochrome c release, resulting in increased ROS and oxidative stress (124)