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Ultrathin sections were cut with a diamond knife using a Leica Ultracut S ultra-microtome (Austria), stained with both methanolic uranyl acetate and lead citrate before viewing in a JEOL 1011 transmission electron microscope (Japan) at 60 kV

In several studies reported that chronic ROS exposure showed not severe liver injury

The participants met on two separate occasions at which time they were given either NAC or placebo capsules

STK11/LKB1 loss of function is associated with global DNA hypomethylation and S-adenosyl-methionine depletion in human lung adenocarcinoma

doi: 10.3389/fcell.2018.00090 Received 31 May 2018 Accepted 25 July 2018 Published 15 August 2018 Volume 6 - 2018 Edited by Concetta Bubici, Brunel University London, United Kingdom Reviewed by Alice Newman, University of Glasgow, United Kingdom

Many studies have linked GPx1 to cancer initiation and progression in various stages of carcinogenesis 41