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Outside the CNS, serotonin is produced in the ENS and released predominantly by enterochromaffin cells (estimated to be up to 90% of the body's serotonin production [169]) of the gut mucosa and immune cells, with influence not only on the ENS but also on the CNS via the GBA [283]

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Incubation of acetone with homogenates of nasal mucosa from mice indicated that acetone was metabolized via a NADPH-dependent pathway in vitro , but no evidence of in vivo metabolism of acetone by the upper respiratory tract was found in mice, rats, guinea-pigs or hamsters (Morris, 1991 )

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and 5-TGGCAAATTCCATGGCACC-3 (sense) and 5-AGAGATGATGACCCTTTTG-3 (antisense) to detect GAPDH mRNAs

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