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This enzymatic process liberates Cbl, allowing it to bind to a glycoprotein known as the intrinsic factor (IF), which is synthesized by gastric parietal cells

[DOI] [PubMed] [Google Scholar] 125.Wang J., Li Y

Meanwhile, GRh3 prevents NRF2 from entering the nucleus, thereby suppressing SLC7A11, resulting in GSH depletion and the accumulation of iron, ROS, and MDA, ultimately triggering ferroptosis in CRC cells [296]

Riegel | Wolle, Montana Pay Dirt: A Guide to the Mining Camps of the Treasure State, reviewed by Nell Murbarger | Oglesby, Manuel Lisa and the Opening of the Missouri River Trade, reviewed by Harold H