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Circulating monocytes adhere to the surface of the artery intima under the impact of endothelial cell adhesion molecules and gradually penetrate the arterial intima ( FIGURE 3 Endothelial dysfunction also causes the lipid composition of the blood to gradually accumulate under the inner membrane

A phase I clinical trial of autologous chimeric antigen receptor (CAR) T cells genetically engineered to secrete IL-12 and to target the MUC16ecto antigen in patients (pts) with MUC16ecto + recurrent high-grade serous ovarian cancer (HGSOC)

SIRT3 suppression resulting from the enhanced -catenin signaling drives glycolysis and promotes hypoxia-induced cell growth in hepatocellular carcinoma cells

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Importantly, if the immune system itself is to be incorporated on-chip, the requirement for autologous integration extends to all tissues involved, ensuring consistency and fidelity of patient-specific responses

FBB were more likely to have a family history of HBV (10% vs