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As described in the previous section, oxidative stress originates mainly from the excessive production of ROS arising from mitochondrial oxidative phosphorylation

311,312 A meta-analysis of findings from 18 randomized controlled trials involving a combined total of 1,184 participants with fibromyalgia found aerobic exercise, strength training, and stretching exercises all decreased pain perception, improved Fibromyalgia Impact Questionnaire scores, and increased physical and mental health-related quality of life