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doi: 10.1158/0008-5472.CAN-13-1641

The fatty acids consumed by the model group were more than four times that of the control group

Singh N, Gurav A, Sivaprakasam S, Brady E, Padia R, Shi H, Thangaraju M, Prasad PD, Manicassamy S, Munn DH, Lee JR, Offermanns S, Ganapathy V (2014) Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis

During this process, tumor cells undergo a transformation from an epithelial phenotype to a more aggressive mesenchymal phenotype, enhancing the ability to evade the effects of the drug and promote survival

doi: 10.31088/CEM2019.8.3.41-47

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