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Compromised antioxidant defenses leading to elevated ROS levels can have detrimental consequences, impacting mitochondrial membrane polarization and jeopardizing T-cell activation and survival, as illustrated in Figure 3 (91)

In a clinical trial designed to evaluate the effects of apple extract (AP) supplements containing PCs on skin pigmentation issues induced by UV exposure in healthy women, participants were randomly assigned to three groups: a low-dose AP group (300 mg/day), a high-dose AP group (600 mg/day), and a placebo group

Journal of Applied Physiology 1997;83(6):2055-2063

In the present study, a marked reduction of intracellular GSH was detected following treatment with BSO

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