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Mol Cell Endocrinol 464, 65-74 (2018)

PDI accelerates disulfide interchange in kinetically trapped intermediates, shuffling these disulfides until the most stable protein configuration is achieved

Unspecified Code In the FY 2022 IPPS/LTCH PPS final rule (86 FR 44940 through 44943), we finalized the implementation of a new Unspecified code edit, effective with discharges on and after April 1, 2022

A simplified snapshot as of mid-2026: FDA-approved (legal by prescription): semaglutide and tirzepatide (GLP-1 medications for weight and metabolic health) and tesamorelin