128,129,220,221 Wei et al found that nobiletin significantly reduced the gene expression levels of IL-6, IL-1, TNF-, matrix metalloproteinase-1 (MMP-1), and matrix metalloproteinase-3 (MMP-3)

Disclosures: Hyunseok Kim: Nothing to Disclose, Ally Hatcher: Nothing to Disclose, Vikrant Rachakonda: Nothing to Disclose, Linda Azab: Nothing to Disclose, Touseef Qureshi: Nothing to Disclose, Lixia Wang: Nothing to Disclose, Ji Hye Min: Nothing to Disclose, Polly Kirsch: Nothing to Disclose, Irene Kim: Nothing to Disclose, Yee Hui Yeo: Nothing to Disclose, Walid Ayoub: Intercept: Speaking and Teaching, Mirum: Grant/Research Support, GSK: Consultant, GSK: Grant/Research Support, Madrigal: Grant/Research Support, Cymabay: Consultant, Ipsen: Grant/Research Support, Zydus: Grant/Research Support, Alexander Kuo: Nothing to Disclose, Hirsh Trivedi: Nothing to Disclose, Aarshi Vipani: Nothing to Disclose, Yun Wang: Nothing to Disclose, Ekihiro Seki: Nippon Zoki: Research Grant Support, Novonordisc: Consultant, Fasiha Kanwal: Nothing to Disclose, Stephen Pandol: Nothing to Disclose, Debiao Li: Nothing to Disclose, Shelly Lu: Nothing to Disclose, Ju Dong Yang: Nothing to Disclose 1469 INCIDENCE AND PREDICTORS OF LONG-TERM RISKS OF CIRRHOSIS AMONG VETERANS WITH ALCOHOL-ASSOCIATED LIVER DISEASE Robert Wong 1 Zeyuan Yang 1 Wei Zhang 2 Brian Lee 3 Ramsey Cheung 4 , 1 VA Palo Alto Healthcare System, 2 Harvard Medical School, 3 Keck School of Medicine, 4 Stanford University Medical Center Background: Alcohol- associated liver disease (ALD) has rapidly emerged as the leading cause of end-stage liver disease requiring liver transplantation among U.S

A noter que ces rsultats sont obtenus avec une formule libration retarde trs spcifique, avec une quantit significative dadditifs (plus de 2/3 de la formule) 4
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PMID 23019153 DOI 10.1002/psc.2455 Editorially curated and source-verified