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doi: 10.1111/j.1368-5031.2005.00669.x 143 OkoduwaSIRMhyaDHAbdulwaliyuIIgiriBEOkoduwaUJArthurDEet al

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This is commonly referred to as neuronal firing. In contrast, influx of negatively charged ions can have inhibitory effects by hyperpolarizing the membrane and thus preventing neuronal firing (15)

Factors that affect alcohol metabolism include: Age As you get older, your metabolism naturally slows down, and your liver becomes less efficient at eliminating alcohol