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This analysis revealed that cells explanted from residual tumors from mice treated with the drug combination presented reduced non-mitochondrial oxygen consumption, basal respiration, maximal respiration, non-ATP linked oxygen consumption (proton leak), ATP production-associated respiration, and spare respiratory capacity, depicting a global reduction in mitochondrial respiratory capacity (Fig

Cardoso, D., Barthlmy, I., Blot, S

(PubMed) Sun, X., Chuang, J.C., Kanchwala, M., Wu, L., Celen, C., Li, L., Liang, H., Zhang, S., Maples, T., Nguyen, L.H., Wang, S.C., Signer, R.A., Sorouri, M., Nassour, I., Liu, X., Xu, J., Wu, M., Zhao, Y., Kuo, Y.C., Wang, Z., Xing, C., and H

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By focusing on restoring mitochondrial integrity through supportive care, precision medicine, or genetic correctionwe can envision a future where HIV treatment goals extend beyond undetectable viral loads to encompass full metabolic and immunological rejuvenation, granting people living with HIV not only longer but healthier lives

Peripheral neuropathy Cisplatin causes a sensory proprioceptive peripheral neuropathy (Mohammad et al