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Furthermore, the inhibition of ferroptosis represents a novel therapeutic target for OA management (152, 153)

The degree of PL quenching was proportional to the concentration of TNT

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The SA- -Gal HI cells were nearly homogeneous, displaying the characteristic flattened shape and enlarged cell size of senescent cells with nuclei marked by senescence-associated heterochromatin foci (SAHF), increased immunoreactivity and delocalization of CDK inhibitor proteins p16 Ink4A and p21 Cip1 , and a disordered cytoskeleton with cytoplasmic filamentous (F) actin and nuclear monomeric (G) actin (Figure 1c)

While the intracellular reduction of Cr(VI) to Cr(III), which mostly occurs in the stomach, is believed to be a cause of genotoxicity and carcinogenicity, extracellular reduction is considered to be a detoxifying mechanism

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