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The first two authors contributed equally to the design and implementation of the study

Furthermore, the GSH-dependent antioxidant enzymes (glutathione peroxidase-1, glutathione reductase, glutathione S-transferase) cooperate and are interconnected reactions that eliminate ROS or controlled the redox state

Future therapeutic approaches may combine ferroptosis-targeted agents with mitochondrial protectants to achieve synergistic effects in alleviating myocardial injury and improving cardiac function ( Figure 3 )

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Logan NA, Vos P D (2015) Bacillus