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Harv Rev Psychiatry 17 , 7286, (2009)

Hepatology 70 (2), 273283

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Most patients become bedridden and develop complications, such as respiratory failure, heart failure, and dysphagia, after the age of 10 years and die around the age of 20 years 2,3

Studies have shown that the rapid angiogenesis, proliferation, and metastasis of tumors are linked to the overexpression of reactive oxygen species (ROS) [26], [27]