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This article walks through cagrilintide's chemical structure from the native amylin starting point through each key modification, explaining why each engineering decision was made and what it means for laboratory use

Association of perivascular localization of aquaporin-4 with cognition and Alzheimer disease in aging brains

In this review, we highlight, beyond the neurotrophic action, novel roles of HGF-MET in synaptogenesis during post-natal brain development and the connection between deregulation of MET expression and developmental disorders such as autism spectrum disorder (ASD)

[vi] To determine the maximum starting dose, it has recommended converting the no observed adverse effect levels (NOAELs) from the conducted animal studies into human equivalent doses (HEDs) using standard factors

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Regulatory Toxicology and Pharmacology, 117 , 104766