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Unlike traditional growth hormone therapies, AOD 9604 operates independently of the hGH receptor

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Its local pharmacological characteristics provide a new idea for the treatment of obesity.AOD 9604, as an anti-obesity polypeptide targeting subcutaneous adipose tissue, achieves the effect of local fat reduction by activating lipolysis and inhibiting fat production

In accordance with this theory is the reported weight loss effect of PYY3-36 when injected in rodents in the fasting state or in the early dark cycle times when NPY is naturally induced (172)

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