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Sorafenib plus triplet therapy with venetoclax, azacitidine and homoharringtonine for refractory/relapsed acute myeloid leukemia with FLT3-ITD: A multicenter phase 2 study

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Intriguingly, functional expression of ABCB1/P-glycoprotein induces hypersensitivity, rather than resistance, to the 8-hydroxyquinoline-derived Mannich base Q4

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Notably, 33.5% of differentially expressed genes (FDR 0.01, fold-change 1.5) were robustly rhythmic in young flies, old flies, or both