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Inhibition of the activation of multiple serine proteases with a cathepsin C inhibitor requires sustained exposure to prevent pro-enzyme processing

doi: 10.1016/j.numecd.2014.03.003 149 SeethalerB.NguyenN

Elevations of endogenous kynurenic acid produce spatial working memory deficits

In particular, the glyoxalase I-catalysed isomerization of hemithioacetals involves the sequential formation of -hemithioacetal, deprotonation to form the enediol intermediate and its enantioselective reprotonation 3 , leading to the formation of enantiopure -hydroxythioesters 4,5,6 (Fig

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