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Moreover, alterations in gait parameters have been consistently observed in individuals with dementia, including reduced gait speed, increased stride time variability, and impaired gait stability, especially under dual-task conditions (Chiaramonte and Cioni, 2021)

Alternative approaches such as psychobiotics may target other brain-gut axis pathways independent of any effect on the intestinal barrier

HER2: human epidermal growth factor receptor 2

A phase I study of temozolomide and everolimus (RAD001) in patients with newly diagnosed and progressive glioblastoma either receiving or not receiving enzyme-inducing anticonvulsants: an NCIC CTG study

Western blot analysis Cellular protein was extracted using cell lysis buffer (150 mM NaCl, 50 mM Tris-HCl (pH 8.0), 1% Triton X-100, 2 mM EDTA, 1 Proteinase Inhibitor), and then quantified by a BCA assay (#P0009, Beyotime, Shanghai, China)

Various external factors could trigger the release of drugs from these engineered liposomes, for instance, variation in the pH or enzymatic activity (134136)