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263:213-8 14 -Tamai I ea J Biol Chem 1998;273:20378-82 15 -Tamai I ea

Predictive value of serum HIF-1 and VEGF for arrhythmia in acute coronary syndrome patients

Curcumin (direct inhibitor of STAT3 and NF-kB activation) 281,282,283 is studied in the combination with PDT and/or PTT/hyperthemia 256,284,285 Curcumin also decreases HSP efficiency in cancer cells 286 (including HSP-70) 256 , effectively suppressing the hypoxic phenotype in tumor tissues and activating the anti-tumor immune system 287,288

[DOI] [PMC free article] [PubMed] [Google Scholar] 342.Turkington R.E., Hukriede N.A., Ho J., Jayasundara N., Sanders A.P

In addition, several studies demonstrated that increased dietary intake of DHA prevents vascular pathology through inhibition of ASM in the retina, leading to an inhibition of retinal endothelial cell activation by inflammatory cytokines and reducing pathological retinal angiogenesis (Busik et al., Sphingolipids Diabetes has also been shown to affect sphingolipid metabolism (Fox et al., 2011)