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Fish JE, Yan MS, Matouk CC, St Bernard R, Ho JJ, Gavryushova A, Srivastava D, Marsden PA (2010) Hypoxic repression of endothelial nitric-oxide synthase transcription is coupled with eviction of promoter histones

In the cAMP/PKA pathway, elevated cAMP levels trigger PKA-mediated phosphorylation of substrates, modulating energy metabolism by promoting glycogen breakdown and fatty acid oxidation to maintain energy balance [31]

During the early inflammatory phase of viral infection, viral matrix metalloproteinases and immune-derived cytokines increase bloodbrain barrier permeability, facilitating viral entry and immune cell infiltration into the central nervous system

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Follow-up visits: mid-window and end-of-window, in person or hybrid depending on stability