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Also, no statistical analysis was conducted for this study, and only five rats were examined microscopically.] In another study, histopathological analysis of the livers of male Wistar rats exposed to aspartame at 1000 mg/kg bw for 180 days (by oral intubation) indicated a statistically significant increase in leukocyte infiltration in rats compared with the control group, but no pathological changes in the liver of rats exposed at 500 mg/kg bw (Abhilash et al., 2011)

Ferguson GP, Booth IR: Importance of glutathione for growth and survival of Escherichia coli cells: detoxification of methylglyoxal and maintenance of intracellular K+

10.1016/j.bioorg.2020.103993 141 LiG

The brain-heart axis: integrative cooperation of neural, mechanical and biochemical pathways

Real-time PCR quantitation of clostridia in feces of autistic children

The Gut Wall: The epithelial cells lining the intestine are metabolically active and contain a significant concentration of drug-metabolizing enzymes, particularly the cytochrome P450 isoform CYP3A4