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Concomitantly, a phase I clinical trial using NSCs derived from fetal cortices, genetically engineered to overexpressed the trophic factor glial cell line-derived neurotrophic factor (GDNF) [155], will be conducted through Californias stem cell agency ( The transplantation of SOD1 G93A fALS rats using a similar approach protected the integrity of motor neuron cell bodies, but failed to preserve neuromuscular junctions or increase the life-span of the animals [155]

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3 Conclusion In this study, a nanozyme comprising g-CN-supported Ru single atoms and atomic clusters was successfully developed through a ligand-mediated polymerization confinement strategy

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Shi S, Tang Y, Zhao Q, et al