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Detoxification and breaking down substances: Methylation is essential in the nervous system, in the production and breakdown of neurotransmitters, and in detoxifying some specific environmental toxicants such as arsenic

They sit near the top of the evidence hierarchy, just below meta-analyses (which combine multiple RCTs)

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GHK-Cu did not release well from the gel comprising carbomer, water and triethanolamine which was finalized during placebo trials

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Cagrilintide the Phase 2 monotherapy trial studied once-weekly doses of 0.3, 0.6, 1.2, 2.4, and 4.5 mg with a dose-escalation period