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We found that (i) lactate transport is critically involved in the neuroprotective effect mediated by neuronal activation in hypoxia, (ii) lactate supplemented in the culture medium had a neuroprotective effect, and (iii) astrocyte stimulation with consequent release of lactate was associated with neuroprotection

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1,2,6,18 Patients with pernicious anemia may have hematologic findings consistent w ith normocytic anemia

The two immune systems and their interactions are intimately involved in the development of ACPA-positive RA, which results in the failed resolution of inflammation (chronic synovitis)