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Lu Z, et al

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Experiments with animals were performed in accordance with the Swiss guidelines for animal care, which conform to the NIH animal care guidelines and approved by Swiss cantonal (Canton de Vaud) and federal veterinary authorities (authorization #3488 to DF)

(15) This meta-analysis also mentioned that the optimal dosage for resveratrol is not clear

Molecules 27:889

Similarly, another study demonstrated nephrotoxicity in colitis mice treated with green tea extract containing 35% EGCG, evidenced by increased serum creatinine levels (a nephropathy biomarker), and elevated expression of antioxidant enzymes (HO-1 and NQO1) and HSP 90 (238)