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Some important terms to understand: Free Radical a molecule with an unpaired electron in its outer orbital

Frontiers in neurology

This ligand-dependent transcription factor belongs to the superfamily of 48 known human nuclear receptors (22)

A total of 28 metabolites were found to be significant features for further analyses based on a log2 fold change cutoff of 1.5 at 10% false-discovery rate (Figure 1A

During this process, cells will produce an imbalance between reactive oxygen species (ROS) generation and the antioxidant defense system, thereby triggering oxidative stress and ultimately leading to kidney damage