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Other forms of cell death (pyroptosis and necrosis) can be differentiated from apoptosis using inhibitors of cell membrane permeabilization (5 mM glycine) and the apoptosis-related cysteine peptidase 1 (CASP1) activation inhibitor 100 M benzyloxycarbonyl-Tyr-Val-Ala-Asp(Omethyl)-fluoromethyl ketone [25]

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It has been reported that AC inhibited the proliferation of HT29 human colon cancer cells in a dose-dependent manner with an IC 50 of approximately 50 g/mL, where it exhibited strong anti-metastatic and anti-invasive effects by inhibiting the Rac family small GTPase 1 (Rac-1), hypoxia-inducible factor-1 alpha (HIF-1), and zinc finger E-box-binding homeobox 1 (Zeb-1) pathways (Seyfi et al