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Third, innovative clinical trials should be meticulously designed, such as "basket trials" or "platform trials" that use biomarker enrichment strategies to rapidly validate the efficacy of targeted strategies in small patient populations

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In addition, drug development targeting the gut-brain axis is in the exploratory phase

Although CS-PDMS films have been developed as laser ultrasound transducers 2325 , our study represents the first instance of engineering them into a sandwich-structure

In particular, iTregs generated in the presence of TGFb and rapamycin led to a polyclonal product enriched in FOXP3 + CD25 + CD4 + T cells that was clinically evaluated, depicting a favourable profile encouraging the phase II component for efficacy assessment [38]

Racial differences in androgen receptor protein expression in men with clinically localized prostate cancer