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Food and Drug Administration (FDA) in 1990 and 1997, respectively, for the treatment of idiopathic growth hormone deficiency (GHD) in children with growth failure, or for evaluating the ability of the growth hormone producing cells, called somatotrophs, of the pituitary gland to secrete growth hormone

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Kraemer et al., 2020) and altering the expression of thousands of genes, many of which are involved in the regulation of skeletal muscle structure, fiber type (Dubois et al., 2013), and mRNA transcription (MacLean et al., 2008) (Figure 1)