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The hydroxyl groups at the C9 (C9-OH) and C8 (C8-OH) of the BP face away from the WC edge of dG

Having identified HSL as a key driver of efferocytosis, we next sought to directly assess how its inhibition impacts the macrophage lipid phenotype

GHK-Cu (glycyl-L-histidyl-L-lysine copper) is a naturally occurring copper-binding tripeptide first identified in human plasma

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By focusing on a fragment rather than the full hormone, researchers can explore signaling domains relevant to metabolic pathways with more targeted experimental design