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Phytochemicals targeting the epigenetic dysregulation in CRC are illustrated in (Figure 3)

The availability of methionine, folate, vitamin B12, and betaine influences the rate of homocysteine remethylation, while the transsulfuration pathway acts as a buffer to prevent homocysteine accumulation

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Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress

Proc Natl Acad Sci USA 2014

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