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Cu ions can induce toxicity in mice if dosage exceeds levels of 35 mg/kg [26]

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Lentiviral particle transduction and shRNA knockdown confirmation by RT-qPCR At 80% confluency, DC2 cells were exposed to 18,000 transducing units of viral particles in culture media containing 8 ug/mL hexadimethrine bromide

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doi: 10.1161/ATVBAHA.109.183707

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Noah Davidsohn, chief scientific officer of Rejuvenate, says the company used gene therapy to add three powerful reprogramming genes to the bodies of mice that were equivalent in age to human 77-year-olds

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Figure 2 3.1 DNA damage repair DNA damage repair, which can maintain the stability of biological organisms, is achieved by homologous recombination (HR), a mechanism for DNA double-strand break repair, and DNA mismatch repair (MMR), which corrects recombination or replication errors by base exchange

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