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In experimental BP in adult mice, both C5-deficient and C5aR1-deficient mice developed significantly less skin lesions compared with wild type animals [72, 110]

The outer membrane protein MARCH5 controls quality control and mitochondrial dynamics [141, 142]

Huang et al., 2025), with approximately 83% of children experiencing at least one episode by the age of three (Teele et al., 1989

The Medical Clinics of North America

Considering that these patients exhibit worse health status compared to non-hospitalized subjects, it is paramount to devote maximum attention to pursuing new adjunctive therapies and thus improving the current therapy protocol employed to this particular group of individuals