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Addressing this question will require conditional genetic models and in vivo imaging approaches to clarify causal interactions across different stages, brain regions, and cell types

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Glutathione, often referred to as the master antioxidant, is a critical component in maintaining optimal health

doi: 10.1007/s10571-023-01388-8 36 WangBWangYZhangJHuCJiangJLiYet al

Immunohistochemistry analysis Mice in different treatment groups were anesthetized with pentobarbital sodium (Sigma-Aldrich, P-010) and perfused with PBS followed by 4% paraformaldehyde in PBS

Similarly, other ligands (triphenylphosphonium, AS1) and gH625 (viral derived peptide for effective delivery) have already been shown to preferentially target astrocytes ( Microglia, the brain's resident immune cells, eliminates dead cells, and debris, secretes neurotrophic factors, and contributes to the overall homeostasis of the CNS (80)