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Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models

GSH-independence can be conferred by mutations at the protomer interface, consistent with GSH binding to protomers driving the formation of pentameric units critical to assembly 16,17

2012;33:e100318

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This downregulation facilitated the dissociation of STIM1 from STING, thereby activating the non-canonical STING signaling pathway and enhancing autophagy in cortical neurons

The complex increases the level of cytoplasmic ROS, which is detected by MPO