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Clinical box A seemingly healthy 45-year-old man with abnormal transaminases A 45-year-old businessman had a routine medical examination, at which he was found to have a slightly enlarged liver

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Note: folinic acid, not folic acid

We included original research ( in vitro , in vivo , or clinical) and high-quality reviews investigating medicinal plants in MAFLD-related liver injury or fibrosis, with mechanistic data involving autophagy

59 Although fungi have been emphasized in recent years, 60,61 the low fungal biomass in the lungs, the small number of fungal taxa, the difficulty in extracting DNA from fungi, the bias of 18S rRNA gene amplification, and the inconsistency in naming make fungal database annotation unsatisfactory