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Additionally, inhibition of NNMT using MNAM resulted in a decline in performance during anaerobic endurance exercise in rats (Zhou et al., 2018)

A key enzyme in AD pathobiology is -site APP-cleaving enzyme 1 (BACE1), which catalyzes A production [142]

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Individuals who are heterozygous for GBA pathogenic variants though have an increased risk of parkinsonism and dementia (Tayebi et al