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Patients randomized to placebo, pemetrexed, and platinum chemotherapy were offered pembrolizumab as a single agent at the time of disease progression

In a randomized, double-blind, placebo-controlled trial, patients with preserved small nerve fiber function as defined by QST had a statistically and clinically significant improvement in pain

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doi: 10.1016/S0378-1135(00)00309-6 46 PhanseY.WuC.-W.VenturinoA

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Nevertheless, both dietary intakes of vitamin B12 and serum concentrations of vitamin B12 were unable to observe significant associations between NAFLD patients and controls in 317 Iranians (44) and 54 participants in Greece (15), respectively