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The authors wish to thank the Smiling Dog Foundation for financial support of this project and to Bastyr University for its administration

It is likely that indeed genetic testing will become the first step in the diagnostic process

A recent drug screening also identified a class I HDAC inhibitor, Vorinostat, as an inducer of ferroptosis in small cell lung cancer (SCLC) and isocitrate dehydrogenase ( IDH1/2 )-mutant brain tumors, suggesting an unique vulnerability that is regulated by histone or non-histone acetylation (84)