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[68] reported the rate of ATP synthesis by Complex V (involved in oxidative phosphorylation) is significantly reduced in ME/CFS lymphoblasts, which is supported by the increased expression of a large number of mitochondrial proteins in ME/CFS

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Furthermore, measurements have shown that human breast tumors display plastic deformation (i.e., permanent deformation when subjected to external forces) [144], likely due to the increased collagen concentration and crosslinking observed in the breast tumor microenvironment which can enhance plasticity [145]