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In another report from BlGGT, its T417S mutant could process considerably with time, while T417K mutant led to complete blockage of maturation, suggesting the importance of hydroxyl group of Thr417 for proper autoprocessing (Lyu et al., 2009)

GLUT1OE also induces broad metabolic reprogramming associated with increased glutathione-mediated resistance to reactive oxygen species, and increased inosine accumulation

For this reason, folic acid supplements may mask vitamin-B12-induced megaloblastic anemia and cause an underlying vitamin B12 deficiency to go undetected ( Megaloblastic anemia is a condition characterized by enlarged red blood cells

( c ) Schematic of the assay to determine the rate of PC synthesis from PE methylation using 100 M methionine-(methyl-d3)

Tan, Lushi [Bioorganic and Medicinal Chemistry, 2018, vol

Lipid metabolism pathways, particularly steroid hormone biosynthesis and cholesterol metabolism, were highly enriched across all three iHLO development phases, indicating the organoids capacity to process lipids, especially cholesterol