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Description

This dysregulation of the PPP in cancer cells makes it a potential target for therapeutic intervention, aiming to disrupt the enhanced production of NADPH and impair the cancer cells' metabolic adaptability

2003 Aug;41(4):271-91

Vogel JU, Cinatl J, Dauletbaev N, et al

Sestrin2 levels in patients with anxiety and depression myocardial infarction was up-regulated and suppressed inflammation and ferroptosis by LKB1-mediated AMPK activation